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AREAS FOR POSSIBLE MISSIONS AND AREAS FOR POSSIBLE INSTITUTIONALISED EUROPEAN PARTNERSHIPS TO BE ESTABLISHED UNDER ARTICLE 185 OR 187 TFEU In accordance with Articles 8 and 12 of this Regulation, the areas for possible missions and possible European Partnerships to be established under Article 185 or 187 TFEU are set out in this Annex. I. Areas for possible missions:

— Missions Area 1: Adaptation to Climate Change, including Societal Transformation.

— Mission Area 2: Cancer.

— Mission Area 3: Healthy Oceans, Seas, Coastal and Inland Waters.

— Mission Area 4: Climate-Neutral and Smart Cities.

— Mission Area 5: Soil Health and Food. Each mission follows the principles set out in Article 8(4) of this Regulation.

II. Areas for possible Institutionalised European Partnerships on the basis of Article 185 or 187 TFEU:

— Partnership Area 1: Faster development and safer use of health innovations for European patients, and global health.

— Partnership Area 2: Advancing key digital and enabling technologies and their use, including but not limited to novel technologies such as artificial intelligence, photonics and quantum technologies.

— Partnership Area 3: European leadership in Metrology including an integrated Metrology system.

— Partnership Area 4: Accelerate competitiveness, safety and environmental performance of Union air traffic, aviation and rail.

— Partnership Area 5: Sustainable, inclusive and circular bio-based solutions.

— Partnership Area 6: Hydrogen and sustainable energy storage technologies with lower environmental footprint and less energy-intensive production.

— Partnership Area 7: Clean, connected, cooperative, autonomous and automated solutions for future mobility demands of people and goods.

— Partnership Area 8: Innovative and R&D intensive SMEs.

The process of assessing the need for an Institutionalised European Partnership in one of the abovementioned Partnership Areas may result in a legislative proposal in accordance with the Commission's right of initiative. Otherwise the respective Partnership Area can also be subject to a European Partnership following point (a) of Article 10(1) or point (b) of Article 10(1) of this Regulation or be implemented by other calls for proposals within this Programme. As the possible areas for Institutionalised European Partnerships cover broad thematic fields, they can, based on the assessed needs, be implemented by more than one European Partnership.